Used: If you were a bag of chips, & I were a battery, you’d be Frito-Lay, and I’d be Ever-Ready…
Heard: Do you eat pills (IE-Extacy)?
What about yours?
WOW that one you use… I might need to steal…
worst one I’ve heard: Yeah I have like 12 STD’s.
Heard: “I’m sorry, I thought that was a Braille nametag”
heard: Have you seen my library card cause im checkin you out!
No one has ever used pick up lines on me… <.< >.>
I got a good answer for one, though.
Line: “how do you like your eggs in the morning?”
Answer: “unfertilized”
One used on me: “Wanna?”
Used to work too. Don’t hear it much anymore though.
Then again, I’m not a 20-year old guy with a van anymore.
Yer sher lookin’ purty in them overalls, sis.
This is quickly turning into the “creepy people” thread!
Was your daddy a drug dealer? 'Cuz dayumn… you’re dope!
You order a club soda and a straw. Put one finger on top of the straw to trap some club soda in it. Carefully, drop one drop onto her sleeve. Then, look her in the eyes and say, “Let me take you home and get you out of those wet clothes before you catch a cold.”
used on me: “Wanna play battleships? You lay down and i’ll blow the f*** outta you!”
used / heard:
“Do you raise chickens? Cause you sure raised my coc k”
“Excuse me ma’am, does this rag smell like chloroform?”
me: “did it hurt?”
her: “when i fell from heaven?”
me: “…what? oh wait i haven’t raped you yet!”
“Nice shoes, wanna f***?”
(that one almost worked)
I was going to post that one!
I wish I was your derivative so I could lie tangent to your curves.
If I was an enzyme I’d be DNA helicase so I could unzip your genes.
There’s also this one from HIMYM.
The lines about math and biochem is alright. 
But the one from HIMYM is lame, it for sure would piss the hell off the paramedic. 
I think that was supposed to be prearranged.
The clip cuts it off, but the “paramedics” are actually actors that Barney hired.
“I saw you on Biggest Loser, and you were hotter then”…
Used on me:
I’ve got lots of ties to tie you up & I can make you cum 5 times
Do you drink milk? Cause it sure did that body good
(only the guy was drunk so it came out “do ya dringh Muhlllllgh”, to which I responded “What???” until he said it like 5 times. It didn’t work for me)