Lenovo Thinkcentre M81 i5 250GB Desktop

My son purchased this PC and has found it won’t boot with either of his larger USB drives attached. It will boot with some other smaller ones. Disabled everything in the boot menu that had to do with USB booting but no luck, it hangs on the splash screen.

Would be interested in knowing if anyone else who purchased this has the same issue. Thanks.

Does anybody have insight into this refurbishing company?

This particular pc?